PEDIG Amblyopia treatment

	Alaska Blind Child Discovery
	A cooperative, charitable research project to vision screen every preschool Alaskan
			Amblyopia Treatment Studies
Home	Dr. Arnold and Diane Armitage did enroll patients in NIH-sponsored clinical trials of amblyopia treatment as Pediatric Eye Disease Investigator Group (PEDIG) Site #04.
ABCD History			PEDIG at JAEB Website		An Alaska ATS patient randomizes himself over the Internet with PEDIG:
Kids Eye Disorders	Amblyopia Treatment Study = ATS
Amblyopia	ATS-1	Atropine vs part-time patch: moderate amblyopia
Vision Screening	ATS-2A	Patch 6 hrs vs full-time: severe amblyopia		To enroll in an ATS trial, children must be diagnosed with amblyopia and NOT have had recent amblyopia therapy. They must have a recent cycloplegic refraction and proper spectacle trial. Each must undergo a standardized acuity test using EVA (surround HOTV or ETDRS) protocol. ALL ATS acuity measurements must be done with the non-tested eye patched. Parents are then offered the option to enroll their amblyopic child into a treatment phase which randomizes the child to one of two accepted doses of treatment; either some form of patching or atropine penalization of the better eye.
Issues	ATS-2B	Patch 2 hrs vs 6 hours: moderate amblyopia
ABCD Clinics	ATS-2C	Spectacles but stop patch/atropine after success 1 year
References	ATS-3	Teens: spectacles vs atropine/patch
Contact ABCD	ATS-4	Atropine: weekend vs daily; moderate amblyopia
	ATS-5	Spectacles alone, then patch 2 hrs vs spectacles
	ATS-6	Patch 2 hours with near vs far activities after specs
PEDIG papers	ATS-7	Bilateral refractive amblyopia; spectacles x 1 year
	ATS-8	Atropine: full specs vs reduced plus		ETS-1 observation of recent-onset esotropia / surgery
	ATS-9	Teen "ATS-1": weekend atropine vs patch 2 hrs		NLD-1-3 compared surgical treatment of tear duct obstruction
	ATS-10 ATS-11 terminated ATS-12 terminated ATS-13 current ATS-14 ATS-15 ATS-16 ATS-17	Bangerter filters for amblyopia Final Ramp-up for residual amblyopia Vision Therapy Pilot Study Spectacles for Strabismic Amblyopia Levodopa Pilot Study Increasing Patching for Amblyopia Augmenting Atropine Treatment for Amblyopia Levodopa for Residual Amblyopia		X01 spectacles for new amblyopic patients Corneal Thickness NLD-2: stent vs balloon for recurrent NLD NLD-3: office now vs OR probe later NLD IXT-1: BLR vs R&R for intermittent exotropia IXT-2: Review in AAP "Pediatrics" 2013
	PEDIG is a collaborative group of academic optometrists, orthoptists and ophthalmologists combined with community pediatric ophthalmologists including Dr. Arnold. PEDIG is located in the JAEB Center in Tampa, Florida and is chaired by Roy Beck, MD, PhD. PEDIG enjoys generous NIH support due to efficient recruitment and care of common pediatric eye disorders such as amblyopia (strabismic and refractive), esotropia and nasolacrimal duct obstruction. In part due to successful screening by ABCD, many young Alaskans have participated in Amblyopia Treatment Study and Esotropia Treatment Study Trials.



Active PEDIG recruiting Investigators: Robert Arnold, Jonathan Holmes, Mike Repka, Nick Sala, David Silbert and Darren Hoover. Dr.s Holmes and Repka oversee PEDIG with Dr. Roy Beck.
			Devoted Leaders of PEDIG and the JAEB Center: Don Evertt (NIH), Roy Beck (JAEB), Jonathan Holmes (Mayo), Ray Kraker (PEDIG), Mike Repka (Johns Hopkins)

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Alaska Blind Child Discovery

Amblyopia Treatment Studies

Active PEDIG recruiting Investigators: Robert Arnold, Jonathan Holmes, Mike Repka, Nick Sala, David Silbert and Darren Hoover. Dr.s Holmes and Repka oversee PEDIG with Dr. Roy Beck.